iPTMnet Report for O94768 (STK17B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94768 / ST17B_HUMAN
Protein Name Serine/threonine-protein kinase 17B
Gene Name Name: STK17B
Synonyms:DRAK2;
Organism Homo sapiens (Human)

PRO ID PR:O94768
DAG View
PRO Name serine/threonine-protein kinase 17B (human)
Definition A serine/threonine-protein kinase 17B that is encoded in the genome of human.
Short Label hSTK17B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94768 (STK17B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation neXtProt   PhosphoSitePlus 17182616, 12966074
S10 Phosphorylation O94768 (STK17B) neXtProt 17182616, 12966074
S12 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P 17182616, 12966074
S12 Phosphorylation O94768 (STK17B) neXtProt 17182616, 12966074
K37 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K62 Acetylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
C90 Methylation IEDB 31844290
K185 Ubiquitination PhosphoSitePlus
C287 Methylation IEDB 31844290
T333 Phosphorylation PhosphoSitePlus
S351 Phosphorylation neXtProt 18084041
S351 Phosphorylation P05129 (PRKCG) neXtProt 18084041
K352 Ubiquitination PhosphoSitePlus


O94768 (STK17B) as PTM Enzyme



Substrate Site Score Source PMID
O94768 (STK17B) S10 neXtProt 17182616, 12966074
O94768 (STK17B) S12 neXtProt 17182616, 12966074
P23443 (RPS6KB1) T412 neXtProt 19342653


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S12 L12 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K37 E37 Biomuta DOID:2998 / testicular cancer [ cosmic ]