iPTMnet Report for O94763 (URI1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94763 / RMP_HUMAN
Protein Name Unconventional prefoldin RPB5 interactor 1
Gene Name Name: URI1
Synonyms:C19orf2,NNX3,PPP1R19,RMP,URI;
Organism Homo sapiens (Human)

PRO ID PR:O94763
DAG View
PRO Name unconventional prefoldin RPB5 interactor 1 (human)
Definition An unconventional prefoldin RPB5 interactor 1 that is encoded in the genome of human.
Short Label hURI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94763 (URI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T8 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K172 Methylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus   RLIMS-P 23667685
T242 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus   RLIMS-P 23667685
S244 Phosphorylation PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
T354 O-Glycosylation GlyGen 23301498, 30379171, 35289036, ...27505673
T354 Phosphorylation PhosphoSitePlus
T355 O-Glycosylation GlyGen 23301498, 30379171, 35289036, ...27505673
T355 Phosphorylation PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S372 Phosphorylation P23443 (RPS6KB1) neXtProt   PhosphoSitePlus   Signor   UniProt 18669648, 17936702, 23186163, ...21397856
T373 Phosphorylation PhosphoSitePlus   UniProt 23186163
S375 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
Y403 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus   RLIMS-P 23667685
S418 Phosphorylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23667685, 23186163
T447 Phosphorylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
T473 Phosphorylation PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
T492 Phosphorylation PhosphoSitePlus
S516 O-Glycosylation GlyGen 23301498, 30379171, 35289036, ...27505673
Site PTM Type PTM Enzyme Score Source PMID
T241 Phosphorylation HPRD 19651622, 17081983, 20068231
T242 Phosphorylation HPRD 19651622, 17081983, 20068231
S243 Phosphorylation HPRD 19651622, 17081983, 20068231
S244 Phosphorylation HPRD 19651622, 17081983, 20068231
S372 Phosphorylation HPRD 18669648, 20068231
S442 Phosphorylation HPRD 18669648
S488 Phosphorylation HPRD 20068231
T492 Phosphorylation HPRD 20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O94763 (URI1) T241 P19388 (POLR2E) inhibited_association eFIP 23667685


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 P13 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S243 F243 Biomuta DOID:363 / uterine cancer [ cosmic ]
T354 I354 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S372 C372 Biomuta DOID:1324 / lung cancer [ cosmic ]
S378 C378 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S408 F408 Biomuta DOID:4159 / skin cancer [ cosmic ]
S440 T440 Biomuta DOID:1612 / breast cancer [ icgc ]
S516 T516 Biomuta DOID:1612 / breast cancer [ cosmic ]
S516 C516 Biomuta DOID:1324 / lung cancer [ cosmic ]