Protein Information

Cytoscape View

UniProt AC / UniProt ID O94760 / DDAH1_HUMAN
Protein Name N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Gene Name Name: DDAH1
Organism Homo sapiens (Human)

PRO ID PR:O94760
DAG View
PRO Name N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (human)
Definition An N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 that is encoded in the genome of human.
Short Label hDDAH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O94760 (DDAH1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 9874257
K34 Acetylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
Y50 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
C222 S-Nitrosylation dbSNO 22178444, 12441345
K247 Ubiquitination PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
C274 S-Nitrosylation dbSNO 22178444, 12441345
Site PTM Type PTM Enzyme Score Source PMID
S261 Phosphorylation HPRD 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T157 N157 Biomuta DOID:3571 / liver cancer [ icgc ]
K247 N247 Biomuta DOID:363 / uterine cancer [ tcga ]