iPTMnet Report for O94760 (DDAH1)
Protein Information
UniProt AC / UniProt ID | O94760 / DDAH1_HUMAN |
Protein Name | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
Gene Name | Name: DDAH1 Synonyms:DDAH; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O94760 |
PRO Name | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (human) |
Definition | An N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 that is encoded in the genome of human. |
Short Label | hDDAH1 |
Category | organism-gene |
O94760 (DDAH1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score3 | UniProt | 19413330, 9874257 | ||
K34 | Acetylation | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y161 | Phosphorylation | score1 | PhosphoSitePlus | |||
C222 | S-Nitrosylation | score2 | dbSNO | 22178444, 12441345 | ||
K247 | Ubiquitination | score1 | PhosphoSitePlus | |||
S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
C274 | S-Nitrosylation | score2 | dbSNO | 22178444, 12441345 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K34 | E34 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K247 | N247 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |