Protein Information

Cytoscape View

UniProt AC / UniProt ID O76094 / SRP72_HUMAN
Protein Name Signal recognition particle subunit SRP72
Gene Name Name: SRP72
Organism Homo sapiens (Human)

PRO ID PR:O76094
DAG View
PRO Name signal recognition particle subunit SRP72 (human)
Definition A signal recognition particle subunit SRP72 that is encoded in the genome of human.
Short Label hSRP72
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O76094 (SRP72) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
S6 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
R90 Methylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
K391 Sumoylation PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
K475 Acetylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
K498 Acetylation PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K515 Ubiquitination PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
T538 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
Y566 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K569 Ubiquitination PhosphoSitePlus
T571 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163
K600 Ubiquitination PhosphoSitePlus
T602 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
T618 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 24275569
S620 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S621 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T624 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S625 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S630 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
T633 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S635 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S637 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T638 Phosphorylation PhosphoSitePlus
S639 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T655 O-Glycosylation GlyGen 32119511, 28510447, 25367160
K656 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T108 Phosphorylation HPRD 19664995
Y566 Phosphorylation HPRD 18669648
T571 Phosphorylation HPRD 18691976, 18669648
S610 Phosphorylation HPRD 19413330
S611 Phosphorylation HPRD 19413330
S616 Phosphorylation HPRD 20068231
T618 Phosphorylation HPRD 19413330, 18691976, 18669648, ...19651622, 20068231
S620 Phosphorylation HPRD 19413330, 18669648, 17081983
S621 Phosphorylation HPRD 19413330, 18691976, 20058876, ...19691289, 19007248, 18669648, 18707149, 20068231
T624 Phosphorylation HPRD 19413330, 17081983, 20058876, ...19651622, 18669648, 18707149, 20068231
S625 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231
S630 Phosphorylation HPRD 19413330, 18669648, 20068231
T633 Phosphorylation HPRD 18669648
S635 Phosphorylation HPRD 18669648, 20068231
S637 Phosphorylation HPRD 18669648
S639 Phosphorylation HPRD 18669648

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:363 / uterine cancer [ tcga ]
K99 T99 Biomuta DOID:363 / uterine cancer [ tcga ]
K99 N99 Biomuta DOID:3571 / liver cancer [ icgc ]
T108 A108 Biomuta DOID:363 / uterine cancer [ tcga ]
K297 N297 Biomuta DOID:3571 / liver cancer [ icgc ]
K391 E391 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S637 F637 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
T638 A638 Biomuta DOID:363 / uterine cancer [ tcga ]