iPTMnet Report for O76090 (BEST1)
Protein Information
| UniProt AC / UniProt ID | O76090 / BEST1_HUMAN |
| Protein Name | Bestrophin-1 |
| Gene Name | Name: BEST1 Synonyms:VMD2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O76090 |
| PRO Name | bestrophin-1 (human) |
| Definition | A bestrophin-1 that is encoded in the genome of human. |
| Short Label | hBEST1 |
| Category | organism-gene |
DAG ViewO76090 (BEST1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y148 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y227 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S358 | Phosphorylation | P17252 (PRKCA) , Q05655 (PRKCD) | score4 | PhosphoSitePlus RLIMS-P Signor | 19635817, 29121962 | |
| T504 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K511 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T536 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y148 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| K511 | T511 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
