iPTMnet Report for O76082 (SLC22A5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O76082 / S22A5_HUMAN
Protein Name Organic cation/carnitine transporter 2
Gene Name Name: SLC22A5
Synonyms:OCTN2;
Organism Homo sapiens (Human)

PRO ID PR:O76082
DAG View
PRO Name organic cation/carnitine transporter 2 (human)
Definition An organic cation/carnitine transporter 2 that is encoded in the genome of human.
Short Label hSLC22A5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O76082 (SLC22A5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N57 N-Glycosylation GlyGen   UniProt 19349973
T88 Phosphorylation PhosphoSitePlus
N91 N-Glycosylation GlyGen   UniProt 24190977, 17509700, 19349973
S93 Phosphorylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
Y486 Phosphorylation PhosphoSitePlus   UniProt 19690332
K543 Ubiquitination PhosphoSitePlus
T550 Phosphorylation PhosphoSitePlus   UniProt 23186163
K553 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T88 P88 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
N91 H91 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K302 E302 Biomuta DOID:10534 / stomach cancer [ cosmic ]