iPTMnet Report for O76071 (CIAO1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O76071 / CIAO1_HUMAN
Protein Name Probable cytosolic iron-sulfur protein assembly protein CIAO1
Gene Name Name: CIAO1
Synonyms:CIA1;
Organism Homo sapiens (Human)

PRO ID PR:O76071
DAG View
PRO Name probable cytosolic iron-sulfur protein assembly protein CIAO1 (human)
Definition A protein CIAO1 that is encoded in the genome of human.
Short Label hCIAO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O76071 (CIAO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Ubiquitination PhosphoSitePlus
S4 Phosphorylation HPRD   PhosphoSitePlus 20068231
C19 Methylation IEDB 31844290
R41 Methylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
C72 Methylation IEDB 31844290
C86 Methylation IEDB 31844290
K90 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
C261 Methylation IEDB 31844290
K332 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K2 T2 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
C19 F19 Biomuta DOID:3571 / liver cancer [ cosmic ]
S57 C57 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
C261 R261 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]