Protein Information

Cytoscape View


UniProt AC / UniProt ID O75955 / FLOT1_HUMAN
Protein Name Flotillin-1
Gene Name Name: FLOT1
Organism Homo sapiens (Human)

PRO ID PR:O75955
DAG View
PRO Name flotillin-1 (human)
Definition A flotillin-1 that is encoded in the genome of human.
Short Label hFLOT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75955 (FLOT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus   UniProt 18691976, 24275569
K51 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
Y56 Phosphorylation P12931 (SRC) PhosphoSitePlus 24983503
K78 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
Y149 Phosphorylation P12931 (SRC) PhosphoSitePlus 24983503
K152 Ubiquitination PhosphoSitePlus
Y160 Phosphorylation P06241 (FYN) PhosphoSitePlus 19258392
S163 Phosphorylation PhosphoSitePlus   UniProt 23186163
K166 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
Y203 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S205 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
K220 Methylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
Y238 Phosphorylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus   RLIMS-P 21399631
K341 Ubiquitination PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S385 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...24275569
T387 Phosphorylation PhosphoSitePlus   UniProt 23186163
K392 Ubiquitination PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation HPRD 18691976, 19007248
S128 Phosphorylation HPRD 20068231
Y203 Phosphorylation HPRD 18083107, 18578522, 18707149
S383 Phosphorylation HPRD 20068231
S385 Phosphorylation HPRD 18669648
T387 Phosphorylation HPRD 19413330
S407 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K126 I126 Biomuta DOID:3963 / thyroid carcinoma [ cosmic ]
Y292 H292 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S315 P315 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S407 R407 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]