Protein Information

Cytoscape View


UniProt AC / UniProt ID O75940 / SPF30_HUMAN
Protein Name Survival of motor neuron-related-splicing factor 30
Gene Name Name: SMNDC1
Synonyms:SMNR,SPF30;
Organism Homo sapiens (Human)

PRO ID PR:O75940
DAG View
PRO Name survival of motor neuron-related-splicing factor 30 (human)
Definition A survival of motor neuron-related-splicing factor 30 that is encoded in the genome of human.
Short Label hSMNDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75940 (SMNDC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K13 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
T67 Phosphorylation PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
R184 Methylation PhosphoSitePlus
S201 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 19664994, ...19690332, 18669648, 19415658, 20068231
S204 Phosphorylation PhosphoSitePlus
T206 Phosphorylation PhosphoSitePlus
T213 Phosphorylation PhosphoSitePlus
K219 Acetylation PhosphoSitePlus   UniProt 19608861
K219 Ubiquitination PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T57 M57 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S63 C63 Biomuta DOID:1324 / lung cancer [ tcga ]
R184 I184 Biomuta DOID:363 / uterine cancer [ tcga ]
K219 N219 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T227 I227 Biomuta DOID:1324 / lung cancer [ cosmic ]