iPTMnet Report for O75935 (DCTN3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75935 / DCTN3_HUMAN
Protein Name Dynactin subunit 3
Gene Name Name: DCTN3
Synonyms:DCTN22;
Organism Homo sapiens (Human)

PRO ID PR:O75935
DAG View
PRO Name dynactin subunit 3 (human)
Definition A dynactin subunit 3 that is encoded in the genome of human.
Short Label hDCTN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75935 (DCTN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
Y22 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
Y72 Phosphorylation PhosphoSitePlus
R75 Methylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
C173 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
K83 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y22 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K55 R55 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R75 H75 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K148 N148 Biomuta DOID:1319 / brain cancer [ cosmic ]