iPTMnet Report for O75934 (BCAS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75934 / SPF27_HUMAN
Protein Name Pre-mRNA-splicing factor SPF27
Gene Name Name: BCAS2
Synonyms:DAM1;
Organism Homo sapiens (Human)

PRO ID PR:O75934
DAG View
PRO Name pre-mRNA-splicing factor SPF27 (human)
Definition A pre-mRNA-splicing factor SPF27 that is encoded in the genome of human.
Short Label hBCAS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75934 (BCAS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
T4 Phosphorylation PhosphoSitePlus
Y23 Phosphorylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
S83 Phosphorylation HPRD   PhosphoSitePlus 20068231
K85 Ubiquitination PhosphoSitePlus
Y87 Phosphorylation PhosphoSitePlus
S93 Phosphorylation HPRD 20068231
S94 Phosphorylation PhosphoSitePlus   UniProt 23186163
K97 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
S187 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...33465208, 34019948
Y193 Phosphorylation PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T4 A4 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S93 F93 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y207 C207 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y207 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]