iPTMnet Report for O75923 (DYSF)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75923 / DYSF_HUMAN
Protein Name Dysferlin
Gene Name Name: DYSF
Synonyms:FER1L1;
Organism Homo sapiens (Human)

PRO ID PR:O75923
DAG View
PRO Name dysferlin (human)
Definition A dysferlin that is encoded in the genome of human.
Short Label hDYSF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75923 (DYSF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y23 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
R79 Methylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
S100 Phosphorylation phospho.ELM 17081983
T166 Phosphorylation PhosphoSitePlus   UniProt 24275569
G167 Phosphorylation UniProt 24275569
S177 Phosphorylation PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus   UniProt 24275569
P198 Phosphorylation UniProt 24275569
S209 Phosphorylation PhosphoSitePlus
K250 Acetylation PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
Y741 Phosphorylation PhosphoSitePlus
K837 Ubiquitination PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
S905 Phosphorylation PhosphoSitePlus
K910 Ubiquitination PhosphoSitePlus
K983 Ubiquitination PhosphoSitePlus
S1267 Phosphorylation PhosphoSitePlus
Y1319 Phosphorylation PhosphoSitePlus
T1384 Phosphorylation PhosphoSitePlus
T1532 Phosphorylation PhosphoSitePlus
K1609 Ubiquitination PhosphoSitePlus
S1611 Phosphorylation IEDB 35494241
T1646 Phosphorylation PhosphoSitePlus
Y1648 Phosphorylation PhosphoSitePlus
Y1650 Phosphorylation PhosphoSitePlus
T1683 Phosphorylation PhosphoSitePlus
Y1684 Phosphorylation PhosphoSitePlus
S1687 Phosphorylation PhosphoSitePlus
T1804 Phosphorylation PhosphoSitePlus
Y1858 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T94 Phosphorylation HPRD 17081983
S96 Phosphorylation HPRD 17081983
S177 Phosphorylation HPRD 20058876
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S164 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
T192 Phosphorylation PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T184 M184 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T192 A192 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
Y197 * Biomuta DOID:3571 / liver cancer [ cosmic ]
T307 I307 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S324 T324 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K413 E413 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T437 M437 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K910 N910 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1532 M1532 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K1609 N1609 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1609 R1609 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y1650 D1650 Biomuta DOID:4606 / bile duct cancer [ cosmic ]