iPTMnet Report for O75914 (PAK3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75914 / PAK3_HUMAN
Protein Name Serine/threonine-protein kinase PAK 3
Gene Name Name: PAK3
Synonyms:OPHN3;
Organism Homo sapiens (Human)

PRO ID PR:O75914
DAG View
PRO Name serine/threonine-protein kinase PAK 3 (human)
Definition A serine/threonine-protein kinase PAK 3 that is encoded in the genome of human.
Short Label hPAK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75914 (PAK3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
N22 N-Glycosylation GlyGen 24190977
S50 Phosphorylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
N121 N-Glycosylation GlyGen 24190977
K124 Ubiquitination PhosphoSitePlus
S154 Phosphorylation PRO   PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
K257 Acetylation PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
K269 Acetylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
Y298 Phosphorylation PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
T428 Phosphorylation PhosphoSitePlus
K433 Acetylation PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
T436 Phosphorylation PRO   PhosphoSitePlus   RLIMS-P 30858169
T440 Phosphorylation PhosphoSitePlus
Y477 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
K535 Acetylation PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S139 Phosphorylation HPRD   phospho.ELM 16204230, 11278486
S139 Phosphorylation O75914 (PAK3) HPRD   phospho.ELM 16204230, 11278486
T421 Phosphorylation HPRD   phospho.ELM 16204230, 11278486
T421 Phosphorylation O75914 (PAK3) HPRD   phospho.ELM 16204230, 11278486
Site PTM Type PTM Enzyme Score Source PMID
T140 Phosphorylation PhosphoSitePlus


O75914 (PAK3) as PTM Enzyme



Substrate Site Score Source PMID
O75914-2 (PAK3) S139 HPRD   phospho.ELM 16204230, 11278486
O75914-2 (PAK3) T421 HPRD   phospho.ELM 16204230, 11278486
P04049 (RAF1) S338 HPRD   neXtProt   phospho.ELM   Signor 11733498, 9234708, 10205168, ...9823899
P04049 (RAF1) S339 neXtProt 9823899
P17600-1 (SYN1) S605 HPRD 12237306
P19429 (TNNI3) S150 phospho.ELM   Signor 12242269, 15769444
Q02750 (MAP2K1) S298 neXtProt 12876277
Q05682 (CALD1) S714 Signor 20858431
Q05682 (CALD1) S744 Signor 20858431
Q16659 (MAPK6) S189 neXtProt 21177870
Q9UM54-1 (MYO6) T405 HPRD 20068231, 11517222


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048693 (hPAK3/Phos:1) pS154,pT436 PRO