iPTMnet Report for O75911 (DHRS3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75911 / DHRS3_HUMAN
Protein Name Short-chain dehydrogenase/reductase 3
Gene Name Name: DHRS3
Synonyms:RDH17,SDR16C1;ORFNames:UNQ2424/PRO4983;
Organism Homo sapiens (Human)

PRO ID PR:O75911
DAG View
PRO Name short-chain dehydrogenase/reductase 3 (human)
Definition A short-chain dehydrogenase/reductase 3 that is encoded in the genome of human.
Short Label hDHRS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75911 (DHRS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K32 Ubiquitination PhosphoSitePlus
R48 Methylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R48 T48 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R48 K48 Biomuta DOID:1324 / lung cancer [ cosmic ]