iPTMnet Report for O75909 (CCNK)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75909 / CCNK_HUMAN
Protein Name Cyclin-K
Gene Name Name: CCNK
Synonyms:CPR4;
Organism Homo sapiens (Human)

PRO ID PR:O75909
DAG View
PRO Name cyclin-K (human)
Definition A cyclin-K that is encoded in the genome of human.
Short Label hCCNK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75909 (CCNK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S324 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 19369195, ...15302935, 20068231
S328 Phosphorylation PhosphoSitePlus
S329 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 20068231
S340 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...29351928, 34019948, 20305658, 28510447
S340 Phosphorylation PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 19369195, 20068231
R580 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K166 Ubiquitination PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation HPRD 18691976, 20068231
S9 Phosphorylation HPRD 18691976
S11 Phosphorylation HPRD 17081983
S324 Phosphorylation HPRD 19651622, 18691976, 15302935, ...20068231
S328 Phosphorylation HPRD 19651622, 18691976, 19664995, ...20068231, 18452278
S329 Phosphorylation HPRD 18691976, 15302935, 19664995, ...19651622, 20068231, 17924679
S340 Phosphorylation HPRD 18691976, 18212344, 18767875, ...19664995, 18452278, 19651622, 18669648, 20166139, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 L11 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S328 R328 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S329 P329 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S329 Y329 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S340 Y340 Biomuta DOID:363 / uterine cancer [ icgc ]