Protein Information

Cytoscape View

UniProt AC / UniProt ID O75899 / GABR2_HUMAN
Protein Name Gamma-aminobutyric acid type B receptor subunit 2 precursor
Gene Name Name: GABBR2
Organism Homo sapiens (Human)

PRO ID PR:O75899
DAG View
PRO Name gamma-aminobutyric acid type B receptor subunit 2 (human)
Definition A gamma-aminobutyric acid type B receptor subunit 2 that is encoded in the genome of human.
Short Label hGABBR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O75899 (GABBR2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S57 Phosphorylation PhosphoSitePlus
N90 N-Glycosylation GlyGen   UniProt 22660477
T200 Phosphorylation PhosphoSitePlus
T202 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
N389 N-Glycosylation GlyGen   UniProt 22660477
N404 N-Glycosylation GlyGen   UniProt 24305054, 22660477
S434 Phosphorylation PhosphoSitePlus
N453 N-Glycosylation GlyGen   UniProt 22660477
K583 Acetylation PhosphoSitePlus
K589 Acetylation PhosphoSitePlus
K768 Ubiquitination PhosphoSitePlus
K772 Ubiquitination PhosphoSitePlus
K801 Ubiquitination PhosphoSitePlus
T813 Phosphorylation HPRD 18452278
T819 Phosphorylation HPRD   PhosphoSitePlus 18510355, 18452278
S884 Phosphorylation phospho.ELM   PhosphoSitePlus 15822905
S893 Phosphorylation P17612 (PRKACA) neXtProt 11976702
S924 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T202 M202 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:11934 / head and neck cancer [ tcga ] DOID:0070003 / blastoma [ cosmic ]
N389 K389 Biomuta DOID:1324 / lung cancer [ cosmic ]
S434 N434 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S434 I434 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S434 G434 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S884 Y884 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ tcga ]