iPTMnet Report for O75899 (GABBR2)
Protein Information
UniProt AC / UniProt ID | O75899 / GABR2_HUMAN |
Protein Name | Gamma-aminobutyric acid type B receptor subunit 2 precursor |
Gene Name | Name: GABBR2 Synonyms:GPR51,GPRC3B; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75899 |
PRO Name | gamma-aminobutyric acid type B receptor subunit 2 (human) |
Definition | A gamma-aminobutyric acid type B receptor subunit 2 that is encoded in the genome of human. |
Short Label | hGABBR2 |
Category | organism-gene |
O75899 (GABBR2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S57 | Phosphorylation | score1 | PhosphoSitePlus | |||
N90 | N-Glycosylation | score3 | GlyGen UniProt | 22660477 | ||
T200 | Phosphorylation | score1 | PhosphoSitePlus | |||
T202 | Phosphorylation | score1 | PhosphoSitePlus | |||
S379 | Phosphorylation | score1 | PhosphoSitePlus | |||
N389 | N-Glycosylation | score3 | GlyGen UniProt | 22660477 | ||
N404 | N-Glycosylation | score4 | GlyGen UniProt | 24305054, 22660477 | ||
S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
N453 | N-Glycosylation | score3 | GlyGen UniProt | 22660477 | ||
K583 | Acetylation | score1 | PhosphoSitePlus | |||
K589 | Acetylation | score1 | PhosphoSitePlus | |||
K768 | Ubiquitination | score1 | PhosphoSitePlus | |||
K772 | Ubiquitination | score1 | PhosphoSitePlus | |||
K801 | Ubiquitination | score1 | PhosphoSitePlus | |||
T813 | Phosphorylation | score0 | HPRD | 18452278 | ||
T819 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18510355, 18452278 | ||
S884 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15822905 | ||
S893 | Phosphorylation | P17612 (PRKACA) | score2 | neXtProt | 11976702 | |
S924 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T202 | M202 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
N389 | K389 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S434 | N434 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S434 | I434 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S434 | G434 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
N453 | S453 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |