iPTMnet Report for O75822 (EIF3J)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75822 / EIF3J_HUMAN
Protein Name Eukaryotic translation initiation factor 3 subunit J
Gene Name Name: EIF3J
Synonyms:EIF3S1;ORFNames:PRO0391;
Organism Homo sapiens (Human)

PRO ID PR:O75822
DAG View
PRO Name eukaryotic translation initiation factor 3 subunit J (human)
Definition A eukaryotic translation initiation factor 3 subunit J that is encoded in the genome of human.
Short Label hEIF3J
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75822 (EIF3J) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 19369195, 21406692, ...22223895, 22814378, 20068231, 17322308
S11 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231, 17322308
S13 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17322308, 20068231, ...17081983
S20 Phosphorylation PhosphoSitePlus   UniProt 17322308
K27 Ubiquitination PhosphoSitePlus
T33 Phosphorylation PhosphoSitePlus
R38 Methylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
T109 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 17322308, 20068231, 17924679
K117 Acetylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S127 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 25887626, 18669648, 23186163, ...20068231
S127 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 25887626
K133 Ubiquitination PhosphoSitePlus
Y143 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
K197 Acetylation PhosphoSitePlus
C207 S-Nitrosylation dbSNO 19483679
S208 Phosphorylation PhosphoSitePlus
K220 Acetylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus
K222 Acetylation PhosphoSitePlus
K223 Acetylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K233 Methylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
K237 Methylation PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus   UniProt 19690332
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD 19413330, 18491316, 17081983, ...20058876, 19651622, 20068231
S13 Phosphorylation HPRD 19413330, 19651622, 18491316, ...17081983, 20068231
T109 Phosphorylation HPRD 19413330, 17322306, 20058876, ...19664994, 19651622, 18669648, 18767875, 20068231, 17924679
S127 Phosphorylation HPRD 19651622, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 E2 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
A2 V2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]