iPTMnet Report for O75815 (BCAR3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75815 / BCAR3_HUMAN
Protein Name Breast cancer anti-estrogen resistance protein 3
Gene Name Name: BCAR3
Synonyms:NSP2,SH2D3B;ORFNames:UNQ271/PRO308;
Organism Homo sapiens (Human)

PRO ID PR:O75815
DAG View
PRO Name breast cancer anti-estrogen resistance protein 3 (human)
Definition A breast cancer anti-estrogen resistance protein 3 that is encoded in the genome of human.
Short Label hBCAR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75815 (BCAR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K5 Methylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S32 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y42 Phosphorylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
K55 Acetylation PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
T72 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
S78 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S83 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T86 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S93 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
T114 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus   RLIMS-P 34169835
K119 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
T130 Phosphorylation IEDB   PhosphoSitePlus 32897882, 32387766
S164 Phosphorylation PhosphoSitePlus
S182 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
T204 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
T268 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S290 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T292 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S315 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
K334 Methylation PhosphoSitePlus   UniProt 24129315
S338 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
S358 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S363 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T368 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S375 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243
S395 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
Y429 Phosphorylation PhosphoSitePlus
R442 Methylation PhosphoSitePlus   UniProt 24129315
T459 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
T619 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation HPRD 18669648
S78 Phosphorylation HPRD 18669648, 20068231
S83 Phosphorylation HPRD 19651622, 18669648, 20068231
T86 Phosphorylation HPRD 18669648
T130 Phosphorylation HPRD 17081983
S179 Phosphorylation HPRD 20068231
S182 Phosphorylation HPRD 18669648, 16964243, 20068231
Y266 Phosphorylation HPRD 17016520, 17389395
S290 Phosphorylation HPRD 18669648, 20068231, 17924679
T292 Phosphorylation HPRD 18669648
S358 Phosphorylation HPRD 18669648
S363 Phosphorylation HPRD 18669648
S375 Phosphorylation HPRD 18669648, 16964243
S471 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 Q5 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S78 F78 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S83 L83 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y266 F266 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T268 I268 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S315 R315 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S332 P332 Biomuta DOID:1319 / brain cancer [ cosmic ]
S338 P338 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S338 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S363 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S420 Y420 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R442 S442 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R442 M442 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]