iPTMnet Report for O75808 (CAPN15)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75808 / CAN15_HUMAN
Protein Name Calpain-15
Gene Name Name: CAPN15
Synonyms:SOLH;
Organism Homo sapiens (Human)

PRO ID PR:O75808
DAG View
PRO Name calpain-15 (human)
Definition A calpain-15 that is encoded in the genome of human.
Short Label hCAPN15
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75808 (CAPN15) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T13 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
K293 Acetylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus   UniProt 23186163
T332 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus   UniProt 23186163
S337 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus   UniProt 23186163
K348 Ubiquitination PhosphoSitePlus
K404 Acetylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
K686 Ubiquitination PhosphoSitePlus
K702 Ubiquitination PhosphoSitePlus
Y708 Phosphorylation PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
S859 Phosphorylation PhosphoSitePlus
K1053 Ubiquitination PhosphoSitePlus
K1066 Ubiquitination PhosphoSitePlus
S1070 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1074 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T13 Phosphorylation HPRD 20068230
S335 Phosphorylation HPRD 19413330, 20068231
S337 Phosphorylation HPRD 20068231
S338 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T332 P332 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K348 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S720 F720 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S859 G859 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1074 A1074 Biomuta DOID:9256 / colorectal cancer [ cosmic ]