iPTMnet Report for O75794 (CDC123)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75794 / CD123_HUMAN
Protein Name Cell division cycle protein 123 homolog
Gene Name Name: CDC123
Synonyms:C10orf7,D123;
Organism Homo sapiens (Human)

PRO ID PR:O75794
DAG View
PRO Name cell division cycle protein 123 homolog (human)
Definition A cell division cycle protein 123 that is encoded in the genome of human.
Short Label hCDC123
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75794 (CDC123) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C9 Methylation IEDB 31844290
K24 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
S60 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18452278
S70 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18452278
K104 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
C170 Methylation IEDB 31844290
C180 Methylation IEDB 31844290
K186 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
Y301 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K135 N135 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y304 H304 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]