iPTMnet Report for O75747 (PIK3C2G)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75747 / P3C2G_HUMAN
Protein Name Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma
Gene Name Name: PIK3C2G
Organism Homo sapiens (Human)

PRO ID PR:O75747
DAG View
PRO Name phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (human)
Definition A phosphatidylinositol 3-kinase C2 domain-containing subunit gamma that is encoded in the genome of human.
Short Label hPIK3C2G
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75747 (PIK3C2G) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S97 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
T274 Phosphorylation PhosphoSitePlus
Y413 Phosphorylation PhosphoSitePlus
Y419 Phosphorylation HPRD   PhosphoSitePlus 17924679
T423 Phosphorylation PhosphoSitePlus
Y428 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
T665 Phosphorylation PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
K806 Acetylation PhosphoSitePlus
Y1338 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S97 F97 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S268 F268 Biomuta DOID:363 / uterine cancer [ tcga ]
S268 Y268 Biomuta DOID:363 / uterine cancer [ tcga ]
Y413 C413 Biomuta DOID:0070003 / blastoma [ cosmic ]
T665 A665 Biomuta DOID:263 / kidney cancer [ tcga ]