iPTMnet Report O75747 PIK3C2G

Protein Information

Cytoscape View

UniProt AC / UniProt ID	O75747 / P3C2G_HUMAN
Protein Name	Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma
Gene Name	Name: PIK3C2G
Organism	Homo sapiens (Human)

PRO ID	PR:O75747 DAG View
PRO Name	phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (human)
Definition	A phosphatidylinositol 3-kinase C2 domain-containing subunit gamma that is encoded in the genome of human.
Short Label	hPIK3C2G
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

O75747 (PIK3C2G) as Substrate

O75747

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S97	Phosphorylation		score1	PhosphoSitePlus
	C230	Methylation		score1	IEDB	31844290
	S268	Phosphorylation		score1	PhosphoSitePlus
	T274	Phosphorylation		score1	PhosphoSitePlus
	Y413	Phosphorylation		score1	PhosphoSitePlus
	Y419	Phosphorylation		score2	HPRD PhosphoSitePlus	17924679
	T423	Phosphorylation		score1	PhosphoSitePlus
	Y428	Phosphorylation		score1	PhosphoSitePlus
	S457	Phosphorylation		score1	PhosphoSitePlus
	T665	Phosphorylation		score1	PhosphoSitePlus
	S697	Phosphorylation		score1	PhosphoSitePlus
	K806	Acetylation		score1	PhosphoSitePlus
	Y1338	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S97	F97	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
C230	S230	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S268	Y268	Biomuta		DOID:363 / uterine cancer [ icgc ]
S268	F268	Biomuta		DOID:363 / uterine cancer [ icgc ]
Y413	C413	Biomuta		DOID:1793 / pancreatic cancer [ cosmic ]
T423	I423	Biomuta		DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
Y1338	C1338	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]