iPTMnet Report for O75683 (SURF6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75683 / SURF6_HUMAN
Protein Name Surfeit locus protein 6
Gene Name Name: SURF6
Synonyms:SURF-6;
Organism Homo sapiens (Human)

PRO ID PR:O75683
DAG View
PRO Name surfeit locus protein 6 (human)
Definition A surfeit locus protein 6 that is encoded in the genome of human.
Short Label hSURF6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75683 (SURF6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
K17 Acetylation PhosphoSitePlus
K61 Acetylation PhosphoSitePlus
K66 Acetylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S74 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19691289, ...19007248, 18669648, 20068231, 17924679
S78 Phosphorylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S138 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 21406692, ...23186163, 19691289, 19664995, 18669648, 19007248, 20068231
K144 Ubiquitination PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
C189 S-Nitrosylation dbSNO 26338901
S206 Phosphorylation HPRD   PhosphoSitePlus 19007248, 20068231, 19691289
T229 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19007248, ...20068231
T232 Phosphorylation HPRD   PhosphoSitePlus 20068231
S248 Phosphorylation PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
Y275 Phosphorylation PhosphoSitePlus
K294 Acetylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K298 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K17 N17 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K17 M17 Biomuta DOID:1324 / lung cancer [ cosmic ]
S133 N133 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T229 K229 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T229 M229 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]