iPTMnet Report for O75665 (OFD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75665 / OFD1_HUMAN
Protein Name Centriole and centriolar satellite protein OFD1
Gene Name Name: OFD1
Synonyms:CXorf5;
Organism Homo sapiens (Human)

PRO ID PR:O75665
DAG View
PRO Name centriole and centriolar satellite protein OFD1 (human)
Definition A centriole and centriolar satellite protein OFD1 that is encoded in the genome of human.
Short Label hOFD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75665 (OFD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K22 Ubiquitination PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K441 Sumoylation PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
Y558 Phosphorylation PhosphoSitePlus
K562 Ubiquitination PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
K632 Ubiquitination PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
Y652 Phosphorylation PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K668 Ubiquitination PhosphoSitePlus
S669 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648
S672 Phosphorylation PhosphoSitePlus
K680 Ubiquitination PhosphoSitePlus
S686 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T718 Phosphorylation PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus   UniProt 23186163
S735 Phosphorylation PhosphoSitePlus   UniProt 33934390
S736 Phosphorylation PhosphoSitePlus
T737 Phosphorylation PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus   UniProt 23186163
S762 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus   UniProt 23186163
T776 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus   UniProt 23186163
S811 Phosphorylation IEDB   PhosphoSitePlus   UniProt 27920218, 23186163
K815 Ubiquitination PhosphoSitePlus
S827 Phosphorylation PhosphoSitePlus
S830 Phosphorylation PhosphoSitePlus
S844 Phosphorylation PhosphoSitePlus
K871 Acetylation PhosphoSitePlus
K888 Methylation PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
K914 Ubiquitination PhosphoSitePlus
S943 Phosphorylation PhosphoSitePlus
S951 Phosphorylation PhosphoSitePlus
S954 Phosphorylation PhosphoSitePlus
K963 Ubiquitination PhosphoSitePlus
S973 Phosphorylation PhosphoSitePlus
S986 Phosphorylation PhosphoSitePlus
S1011 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S171 Phosphorylation HPRD 18491316
S663 Phosphorylation HPRD 20068231
S669 Phosphorylation HPRD 19651622, 18669648, 20068231
S686 Phosphorylation HPRD 18669648
S720 Phosphorylation HPRD 19691289
S735 Phosphorylation HPRD 19691289, 20068231
S736 Phosphorylation HPRD 20068231
S774 Phosphorylation HPRD 19691289
T776 Phosphorylation HPRD 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K22 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S68 P68 Biomuta DOID:1612 / breast cancer [ cosmic ]
S171 F171 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S195 Y195 Biomuta DOID:363 / uterine cancer [ icgc ]
K358 N358 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K533 N533 Biomuta DOID:263 / kidney cancer [ cosmic ]
S620 F620 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
S620 P620 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S663 G663 Biomuta DOID:363 / uterine cancer [ icgc ]
K668 N668 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S669 N669 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K680 N680 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K815 N815 Biomuta DOID:3571 / liver cancer [ cosmic ]
S830 T830 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K963 E963 Biomuta DOID:363 / uterine cancer [ icgc ]
S973 L973 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]