iPTMnet Report for O75635 (SERPINB7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75635 / SPB7_HUMAN
Protein Name Serpin B7
Gene Name Name: SERPINB7
Organism Homo sapiens (Human)

PRO ID PR:O75635
DAG View
PRO Name serpin B7 (human)
Definition A serpin B7 that is encoded in the genome of human.
Short Label hSERPINB7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75635 (SERPINB7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N68 N-Glycosylation GlyGen 23090970, 24190977
N88 N-Glycosylation GlyGen 23090970, 24190977
N148 N-Glycosylation GlyGen 23090970, 24190977
K196 Methylation PhosphoSitePlus
N215 N-Glycosylation GlyGen 23090970, 24190977
S217 Phosphorylation PhosphoSitePlus   UniProt 20068231
S223 Phosphorylation PhosphoSitePlus   UniProt 20068231
T262 Phosphorylation PhosphoSitePlus
T337 Phosphorylation PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S217 Phosphorylation HPRD 20068231
S223 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K196 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K196 E196 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
N215 K215 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S217 F217 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S217 Y217 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S342 C342 Biomuta DOID:10534 / stomach cancer [ cosmic ]