iPTMnet Report for O75626 (PRDM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75626 / PRDM1_HUMAN
Protein Name PR domain zinc finger protein 1
Gene Name Name: PRDM1
Synonyms:BLIMP1;
Organism Homo sapiens (Human)

PRO ID PR:O75626
DAG View
PRO Name PR domain zinc finger protein 1 (human)
Definition A PR domain zinc finger protein 1 that is encoded in the genome of human.
Short Label hPRDM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75626 (PRDM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
T23 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
R371 Methylation PhosphoSitePlus
S448 O-Glycosylation GlyGen 34907035
S472 O-Glycosylation GlyGen 34907035
S511 Phosphorylation PhosphoSitePlus
T518 Phosphorylation PhosphoSitePlus
T534 O-Glycosylation GlyGen 31492838
S641 Phosphorylation PhosphoSitePlus
K678 Acetylation PhosphoSitePlus
K816 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S21 F21 Biomuta DOID:4159 / skin cancer [ cosmic ]
S272 L272 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S288 G288 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T359 A359 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T359 M359 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R371 W371 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
R371 Q371 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R371 L371 Biomuta DOID:3571 / liver cancer [ cosmic ]
T518 M518 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
K678 T678 Biomuta [ cosmic ]
K678 E678 Biomuta DOID:2394 / ovarian cancer [ cosmic ]