Protein Information

Cytoscape View


UniProt AC / UniProt ID O75608 / LYPA1_HUMAN
Protein Name Acyl-protein thioesterase 1
Gene Name Name: LYPLA1
Synonyms:APT1,LPL1;
Organism Homo sapiens (Human)

PRO ID PR:O75608
DAG View
PRO Name acyl-protein thioesterase 1 (human)
Definition An acyl-protein thioesterase 1 that is encoded in the genome of human.
Short Label hLYPLA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75608 (LYPLA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K97 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus   RLIMS-P 29648538
S210 Phosphorylation PhosphoSitePlus   RLIMS-P 29648538
C211 S-Nitrosylation dbSNO 26338901
K224 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S210 L210 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1324 / lung cancer [ icgc, tcga ]