iPTMnet Report for O75554 (WBP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75554 / WBP4_HUMAN
Protein Name WW domain-binding protein 4
Gene Name Name: WBP4
Synonyms:FBP21;
Organism Homo sapiens (Human)

PRO ID PR:O75554
DAG View
PRO Name WW domain-binding protein 4 (human)
Definition A WW domain-binding protein 4 that is encoded in the genome of human.
Short Label hWBP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75554 (WBP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Methylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
S227 Phosphorylation PhosphoSitePlus   UniProt 23186163
S229 Phosphorylation PhosphoSitePlus   UniProt 23186163
S258 Phosphorylation PhosphoSitePlus
S262 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 24275569
S277 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
K301 Sumoylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
T343 O-Glycosylation GlyGen 31373491
S344 O-Glycosylation GlyGen 31373491
Site PTM Type PTM Enzyme Score Source PMID
S220 Phosphorylation HPRD 20068231
S262 Phosphorylation HPRD 19651622
T266 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S51 I51 Biomuta [ cosmic ]
Y76 C76 Biomuta DOID:363 / uterine cancer [ icgc ]
S213 L213 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S220 F220 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S258 R258 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S344 Y344 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S344 F344 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]