iPTMnet Report for O75529 (TAF5L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75529 / TAF5L_HUMAN
Protein Name TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
Gene Name Name: TAF5L
Synonyms:PAF65B;
Organism Homo sapiens (Human)

PRO ID PR:O75529
DAG View
PRO Name TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (human)
Definition A TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L that is encoded in the genome of human.
Short Label hTAF5L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75529 (TAF5L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
T443 Phosphorylation PhosphoSitePlus
K448 Acetylation PhosphoSitePlus
T449 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S25 L25 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T443 M443 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T443 S443 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S460 L460 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S460 A460 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K504 T504 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]