Protein Information

Cytoscape View


UniProt AC / UniProt ID O75489 / NDUS3_HUMAN
Protein Name NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor
Gene Name Name: NDUFS3
Organism Homo sapiens (Human)

PRO ID PR:O75489
DAG View
PRO Name NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (human)
Definition An NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial that is encoded in the genome of human.
Short Label hNDUFS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75489 (NDUFS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S38 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
Y64 Phosphorylation PhosphoSitePlus
T115 Phosphorylation PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
Y191 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
K232 Acetylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K264 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T46 A46 Biomuta DOID:10534 / stomach cancer [ tcga ]
K144 N144 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1612 / breast cancer [ icgc ]
T151 M151 Biomuta DOID:363 / uterine cancer [ cosmic ]
T189 R189 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S237 N237 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]