Protein Information

Cytoscape View

UniProt AC / UniProt ID O75487 / GPC4_HUMAN
Protein Name Glypican-4 precursor
Gene Name Name: GPC4
Organism Homo sapiens (Human)

PRO ID PR:O75487
DAG View
PRO Name glypican-4 (human)
Definition A glypican-4 that is encoded in the genome of human.
Short Label hGPC4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O75487 (GPC4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
Y186 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus   UniProt 21406692
T375 O-Glycosylation GlyGen   PhosphoSitePlus 30459171
T376 O-Glycosylation PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S39 P39 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
T375 N375 Biomuta DOID:363 / uterine cancer [ tcga ]
T376 I376 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S473 R473 Biomuta DOID:3571 / liver cancer [ icgc ]