iPTMnet Report for O75487 (GPC4)
Protein Information
| UniProt AC / UniProt ID | O75487 / GPC4_HUMAN |
| Protein Name | Glypican-4 precursor |
| Gene Name | Name: GPC4 ORFNames:UNQ474/PRO937; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75487 |
| PRO Name | glypican-4 (human) |
| Definition | A glypican-4 that is encoded in the genome of human. |
| Short Label | hGPC4 |
| Category | organism-gene |
DAG ViewO75487 (GPC4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S357 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
| T375 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171, 25813380 | ||
| T376 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T380 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S381 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T472 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S473 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S39 | P39 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| S357 | P357 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T375 | N375 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T376 | I376 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T380 | I380 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] |
