iPTMnet Report for O75486 (SUPT3H)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75486 / SUPT3_HUMAN
Protein Name Transcription initiation protein SPT3 homolog
Gene Name Name: SUPT3H
Synonyms:SPT3;
Organism Homo sapiens (Human)

PRO ID PR:O75486
DAG View
PRO Name transcription initiation protein SPT3 homolog (human)
Definition A transcription initiation protein SPT3 that is encoded in the genome of human.
Short Label hSUPT3H
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75486 (SUPT3H) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T4 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
T13 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K123 Sumoylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K163 Sumoylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 C7 Biomuta DOID:1324 / lung cancer [ cosmic ]
S179 L179 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S252 I252 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]