iPTMnet Report for O75477 (ERLIN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75477 / ERLN1_HUMAN
Protein Name Erlin-1
Gene Name Name: ERLIN1
Synonyms:C10orf69;
Organism Homo sapiens (Human)

PRO ID PR:O75477
DAG View
PRO Name erlin-1 (human)
Definition An erlin-1 that is encoded in the genome of human.
Short Label hERLIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75477 (ERLIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
N108 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
K115 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus
K269 Acetylation PhosphoSitePlus   UniProt 19608861
K269 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
S293 Phosphorylation IEDB 32357974
C312 Methylation IEDB 31844290
S326 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20068231
S329 Phosphorylation HPRD 20068231
K330 Ubiquitination PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N108 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N108 K108 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
K201 R201 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S326 L326 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S329 Y329 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S329 F329 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]