iPTMnet Report O75460 ERN1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	O75460 / ERN1_HUMAN
Protein Name	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor
Gene Name	Name: ERN1 Synonyms:IRE1;
Organism	Homo sapiens (Human)

PRO ID	PR:O75460 DAG View
PRO Name	serine/threonine-protein kinase/endoribonuclease IRE1 (human)
Definition	A serine/threonine-protein kinase/endoribonuclease IRE1 that is encoded in the genome of human.
Short Label	hERN1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

O75460 (ERN1) as Substrate

O75460

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T49	Phosphorylation		score1	PhosphoSitePlus
	T132	Phosphorylation		score1	PhosphoSitePlus
	Y161	Phosphorylation		score1	PhosphoSitePlus
	Y166	Phosphorylation		score1	PhosphoSitePlus
	Y179	Phosphorylation		score1	PhosphoSitePlus
	T283	Phosphorylation		score1	PhosphoSitePlus
	Y289	Phosphorylation		score1	PhosphoSitePlus
	K374	Acetylation		score1	PhosphoSitePlus
	S533	Phosphorylation		score1	PhosphoSitePlus
	S536	Phosphorylation		score1	PhosphoSitePlus
	S544	Phosphorylation		score1	PhosphoSitePlus
	S548	Phosphorylation		score1	PhosphoSitePlus
	S551	Phosphorylation		score1	PhosphoSitePlus
	Y628	Phosphorylation	O75460 (ERN1)	score3	PhosphoSitePlus RLIMS-P	25968568
	K633	Ubiquitination		score1	PhosphoSitePlus
	S724	Phosphorylation	O75460 (ERN1)	score4	neXtProt PhosphoSitePlus RLIMS-P	24853418, 24205197, 21911379, ...24704861, 25870107, 21317875, 22852048, 26325176, 25692299, 24330607, 27009865, 25685256, 26568450
	S726	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	24704861
	S729	Phosphorylation		score1	PhosphoSitePlus
	T973	Phosphorylation		score2	PhosphoSitePlus UniProt	19369195

O75460 (ERN1) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	O75460 (ERN1)	Y628	score2	PhosphoSitePlus	25968568
	O75460 (ERN1)	S724	score2	neXtProt	21317875