iPTMnet Report for O75398 (DEAF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75398 / DEAF1_HUMAN
Protein Name Deformed epidermal autoregulatory factor 1 homolog
Gene Name Name: DEAF1
Synonyms:SPN,ZMYND5;
Organism Homo sapiens (Human)

PRO ID PR:O75398
DAG View
PRO Name deformed epidermal autoregulatory factor 1 homolog (human)
Definition A deformed epidermal autoregulatory factor 1 that is encoded in the genome of human.
Short Label hDEAF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75398 (DEAF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
S176 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163
T179 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
T312 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
T432 Phosphorylation PhosphoSitePlus   UniProt 23186163
S448 Phosphorylation PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
Y483 Phosphorylation PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S176 Phosphorylation HPRD 19413330, 15302935
T179 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T171 P171 Biomuta DOID:1612 / breast cancer [ cosmic ]
K191 E191 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T312 P312 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T312 I312 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S318 F318 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S318 T318 Biomuta DOID:9256 / colorectal cancer [ cosmic ]