iPTMnet Report for O75391 (SPAG7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75391 / SPAG7_HUMAN
Protein Name Sperm-associated antigen 7
Gene Name Name: SPAG7
Organism Homo sapiens (Human)

PRO ID PR:O75391
DAG View
PRO Name sperm-associated antigen 7 (human)
Definition A sperm-associated antigen 7 that is encoded in the genome of human.
Short Label hSPAG7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75391 (SPAG7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
S11 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
S57 Phosphorylation HPRD   PhosphoSitePlus 20068231
S63 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
Y103 Phosphorylation HPRD   PhosphoSitePlus 19413330
K109 Ubiquitination PhosphoSitePlus
S114 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 23186163
Y121 Phosphorylation HPRD 17693683
K139 Ubiquitination PhosphoSitePlus
S158 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18767875, 19664994, ...18669648, 20068231
S161 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y163 Phosphorylation PhosphoSitePlus
K166 Acetylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K177 Methylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
Y189 Phosphorylation PhosphoSitePlus
C191 Methylation IEDB 31844290
C191 S-Nitrosylation dbSNO 26338901
K197 Acetylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus   UniProt 23186163
S219 Phosphorylation PhosphoSitePlus
S227 O-Glycosylation GlyGen 23301498, 34019948, 30620550, ...35132862, 31373491


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K45 R45 Biomuta DOID:3571 / liver cancer [ cosmic, icgc, tcga ]
S57 L57 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K67 N67 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]