iPTMnet Report for O75382 (TRIM3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75382 / TRIM3_HUMAN
Protein Name Tripartite motif-containing protein 3
Gene Name Name: TRIM3
Synonyms:BERP,RNF22,RNF97;
Organism Homo sapiens (Human)

PRO ID PR:O75382
DAG View
PRO Name tripartite motif-containing protein 3 (human)
Definition A tripartite motif-containing protein 3 that is encoded in the genome of human.
Short Label hTRIM3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75382 (TRIM3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S7 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S23 Phosphorylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus   UniProt 23186163
S437 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S443 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
Y457 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
R615 Methylation PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20166139
S437 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 I23 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S427 A427 Biomuta DOID:363 / uterine cancer [ icgc ]
S427 F427 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S437 F437 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S437 Y437 Biomuta DOID:4159 / skin cancer [ cosmic ]
R615 S615 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R615 C615 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]