iPTMnet Report for O75381 (PEX14)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75381 / PEX14_HUMAN
Protein Name Peroxisomal membrane protein PEX14
Gene Name Name: PEX14
Organism Homo sapiens (Human)

PRO ID PR:O75381
DAG View
PRO Name peroxisomal membrane protein PEX14 (human)
Definition A peroxisomal membrane protein PEX14 that is encoded in the genome of human.
Short Label hPEX14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75381 (PEX14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 25944712
T16 Phosphorylation PhosphoSitePlus
K34 Acetylation PhosphoSitePlus   UniProt 19608861
K34 Ubiquitination PhosphoSitePlus
S44 Phosphorylation IEDB   PhosphoSitePlus 24616531
K195 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 32854114, 32831175
S234 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
S247 Phosphorylation RLIMS-P 32854114
S249 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
S286 O-Glycosylation GlyGen 25813380
S286 Phosphorylation PhosphoSitePlus
T287 O-Glycosylation GlyGen 25813380
T289 Phosphorylation PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
S335 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 32854114, 17081983
R351 Methylation PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S232 Phosphorylation HPRD 20068231
S234 Phosphorylation HPRD 20068231
T287 Phosphorylation HPRD 17081983
T289 Phosphorylation HPRD 17081983
S335 Phosphorylation HPRD 17081983


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O75381 (PEX14) S232 P04762 (Cat) inhibited_association eFIP 32831175


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S265 L265 Biomuta DOID:1612 / breast cancer [ cosmic ]
S286 P286 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R351 L351 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R351 W351 Biomuta DOID:9256 / colorectal cancer [ cosmic ]