Protein Information

Cytoscape View


UniProt AC / UniProt ID O75368 / SH3L1_HUMAN
Protein Name SH3 domain-binding glutamic acid-rich-like protein
Gene Name Name: SH3BGRL
Organism Homo sapiens (Human)

PRO ID PR:O75368
DAG View
PRO Name SH3 domain-binding glutamic acid-rich-like protein (human)
Definition An SH3 domain-binding glutamic acid-rich-like protein that is encoded in the genome of human.
Short Label hSH3BGRL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75368 (SH3BGRL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K37 Acetylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
Y63 Phosphorylation PhosphoSitePlus
Y79 Phosphorylation PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
K111 Acetylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 P13 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S13 F13 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
T14 A14 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K19 T19 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K31 Q31 Biomuta DOID:4362 / cervical cancer [ tcga ]