iPTMnet Report for O75354 (ENTPD6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75354 / ENTP6_HUMAN
Protein Name Ectonucleoside triphosphate diphosphohydrolase 6
Gene Name Name: ENTPD6
Synonyms:CD39L2,IL6ST2;
Organism Homo sapiens (Human)

PRO ID PR:O75354
DAG View
PRO Name ectonucleoside triphosphate diphosphohydrolase 6 (human)
Definition An ectonucleoside triphosphate diphosphohydrolase 6 that is encoded in the genome of human.
Short Label hENTPD6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75354 (ENTPD6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K31 Ubiquitination PhosphoSitePlus
Y45 Phosphorylation PhosphoSitePlus
S89 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T93 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
K136 Methylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
N220 N-Glycosylation GlyGen   UniProt 14529283
N284 N-Glycosylation GlyGen   UniProt 14529283
K316 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S238 Phosphorylation HPRD 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S89 R89 Biomuta DOID:1612 / breast cancer [ cosmic ]
T93 I93 Biomuta DOID:1324 / lung cancer [ cosmic ]
S238 N238 Biomuta DOID:9256 / colorectal cancer [ cosmic ]