Protein Information

Cytoscape View

UniProt AC / UniProt ID O75347 / TBCA_HUMAN
Protein Name Tubulin-specific chaperone A
Gene Name Name: TBCA
Organism Homo sapiens (Human)

PRO ID PR:O75347
DAG View
PRO Name tubulin-specific chaperone A (human)
Definition A tubulin-specific chaperone A that is encoded in the genome of human.
Short Label hTBCA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O75347 (TBCA) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K10 Ubiquitination PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K28 Acetylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
R61 Methylation PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
K86 Acetylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
K95 Acetylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S60 Phosphorylation HPRD 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K10 N10 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K36 N36 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1612 / breast cancer [ tcga ]
K36 R36 Biomuta DOID:3277 / thymus cancer [ tcga ]
K39 Q39 Biomuta DOID:363 / uterine cancer [ tcga ]
Y48 D48 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S60 Y60 Biomuta DOID:3571 / liver cancer [ icgc ]