iPTMnet Report for O75346 (ZNF253)
Protein Information
| UniProt AC / UniProt ID | O75346 / ZN253_HUMAN |
| Protein Name | Zinc finger protein 253 |
| Gene Name | Name: ZNF253 Synonyms:BMZF1,ZNF411; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75346 |
| PRO Name | zinc finger protein 253 (human) |
| Definition | A zinc finger protein 253 that is encoded in the genome of human. |
| Short Label | hZNF253 |
| Category | organism-gene |
O75346 (ZNF253) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| C20 | Methylation | score1 | IEDB | 31844290 | ||
| S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C146 | Methylation | score1 | IEDB | 31844290 | ||
| T188 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| T189 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| T195 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K198 | Sumoylation | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T223 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K226 | Sumoylation | score1 | PhosphoSitePlus | |||
| K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K248 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T251 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K254 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K257 | Sumoylation | score1 | PhosphoSitePlus | |||
| K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K263 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T279 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K282 | Sumoylation | score1 | PhosphoSitePlus | |||
| K282 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K285 | Sumoylation | score1 | PhosphoSitePlus | |||
| K285 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K319 | Acetylation | score1 | PhosphoSitePlus | |||
| T335 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K338 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K341 | Sumoylation | score1 | PhosphoSitePlus | |||
| K341 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T363 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K366 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T391 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T417 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T419 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K425 | Sumoylation | score1 | PhosphoSitePlus | |||
| K425 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S432 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T438 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T441 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| T447 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K453 | Sumoylation | score1 | PhosphoSitePlus | |||
| K453 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C146 | Y146 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K248 | R248 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K248 | I248 | Biomuta | [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K257 | T257 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K341 | R341 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| T417 | I417 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:2998 / testicular cancer [ cosmic ] | |
| K422 | R422 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S437 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K453 | R453 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] |
DAG View