Protein Information

Cytoscape View


UniProt AC / UniProt ID O75342 / LX12B_HUMAN
Protein Name Arachidonate 12-lipoxygenase, 12R-type
Gene Name Name: ALOX12B
Organism Homo sapiens (Human)

PRO ID PR:O75342
DAG View
PRO Name arachidonate 12-lipoxygenase, 12R-type (human)
Definition An arachidonate 12-lipoxygenase, 12R-type that is encoded in the genome of human.
Short Label hALOX12B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75342 (ALOX12B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation PhosphoSitePlus
T10 Phosphorylation HPRD   PhosphoSitePlus 20068231
T18 Phosphorylation HPRD   PhosphoSitePlus 20068231
R170 Methylation PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
T326 Phosphorylation PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
Y496 Phosphorylation PhosphoSitePlus
Y497 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R170 C170 Biomuta DOID:0060119 / pharynx cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ icgc, tcga ]
R170 G170 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S330 R330 Biomuta DOID:1115 / sarcoma [ tcga ]