iPTMnet Report for O75340 (PDCD6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75340 / PDCD6_HUMAN
Protein Name Programmed cell death protein 6
Gene Name Name: PDCD6
Synonyms:ALG2;
Organism Homo sapiens (Human)

PRO ID PR:O75340
DAG View
PRO Name programmed cell death protein 6 (human)
Definition A programmed cell death protein 6 that is encoded in the genome of human.
Short Label hPDCD6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75340 (PDCD6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
S5 Phosphorylation PhosphoSitePlus
R34 Methylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
T58 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
R74 Methylation PhosphoSitePlus
K77 Methylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
K90 Methylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y124 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:3571 / liver cancer [ cosmic ]
S44 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S67 L67 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R74 S74 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R74 H74 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S83 T83 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S83 G83 Biomuta DOID:10534 / stomach cancer [ cosmic ]