iPTMnet Report for O75335 (PPFIA4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75335 / LIPA4_HUMAN
Protein Name Liprin-alpha-4
Gene Name Name: PPFIA4
Synonyms:KIAA0897;
Organism Homo sapiens (Human)

PRO ID PR:O75335
DAG View
PRO Name liprin-alpha-4 (human)
Definition A liprin-alpha-4 that is encoded in the genome of human.
Short Label hPPFIA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75335 (PPFIA4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T212 Phosphorylation PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
T609 O-Glycosylation GlyGen 30379171, 28657654
S684 Phosphorylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus
S703 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
K751 Acetylation PhosphoSitePlus
K754 Acetylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus
S866 Phosphorylation PhosphoSitePlus
T1103 Phosphorylation PhosphoSitePlus
S1120 Phosphorylation PhosphoSitePlus
R1133 Methylation PhosphoSitePlus
S1151 Phosphorylation PhosphoSitePlus
T1152 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T609 A609 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S703 F703 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S704 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K751 N751 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S866 L866 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
R1133 C1133 Biomuta DOID:363 / uterine cancer [ icgc ]