iPTMnet Report for O75334 (PPFIA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75334 / LIPA2_HUMAN
Protein Name Liprin-alpha-2
Gene Name Name: PPFIA2
Organism Homo sapiens (Human)

PRO ID PR:O75334
DAG View
PRO Name liprin-alpha-2 (human)
Definition A liprin-alpha-2 that is encoded in the genome of human.
Short Label hPPFIA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75334 (PPFIA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S151 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
T315 O-Glycosylation GlyGen 30379171, 29237092
T468 Phosphorylation PhosphoSitePlus
T474 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
S715 Phosphorylation PhosphoSitePlus
T728 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
K828 Acetylation PhosphoSitePlus
K831 Acetylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
T855 Phosphorylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
S966 Phosphorylation PhosphoSitePlus
T972 Phosphorylation PhosphoSitePlus
T975 Phosphorylation PhosphoSitePlus
S1098 Phosphorylation PhosphoSitePlus
S1215 Phosphorylation PhosphoSitePlus
T1218 Phosphorylation PhosphoSitePlus
T1227 Phosphorylation PhosphoSitePlus
T1237 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S163 F163 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K229 Q229 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T468 M468 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T474 N474 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S476 F476 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S712 L712 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S715 N715 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T728 N728 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S731 N731 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S731 C731 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S832 F832 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S935 F935 Biomuta DOID:1324 / lung cancer [ cosmic ]
S966 R966 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T972 I972 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1215 F1215 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1218 I1218 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T1237 A1237 Biomuta DOID:9256 / colorectal cancer [ cosmic ]