iPTMnet Report for O75330 (HMMR)
Protein Information
| UniProt AC / UniProt ID | O75330 / HMMR_HUMAN |
| Protein Name | Hyaluronan mediated motility receptor |
| Gene Name | Name: HMMR Synonyms:IHABP,RHAMM; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75330 |
| PRO Name | hyaluronan mediated motility receptor (human) |
| Definition | A hyaluronan mediated motility receptor that is encoded in the genome of human. |
| Short Label | hHMMR |
| Category | organism-gene |
O75330 (HMMR) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 16565220 | ||
| S41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S65 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T110 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T198 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K338 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S344 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C361 | Methylation | score1 | IEDB | 31844290 | ||
| K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K489 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K604 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K635 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S656 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K696 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T703 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 22110403, 23186163, 28993511, ... | ||
| C712 | Methylation | score1 | IEDB | 31844290 | ||
| Y713 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C719 | Methylation | score1 | IEDB | 31844290 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S20 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 16565220, ... | ||
| S65 | Phosphorylation | score0 | HPRD | 19007248 | ||
| T110 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S353 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S354 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T703 | Phosphorylation | score0 | HPRD | 20068231, 16565220 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S20 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 16565220, ... | ||
| S65 | Phosphorylation | score0 | HPRD | 19007248 | ||
| T95 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S338 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S339 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T688 | Phosphorylation | score0 | HPRD | 20068231, 16565220 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K221 | E221 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y250 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K251 | T251 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S344 | A344 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| C361 | G361 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K489 | N489 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S656 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| T688 | I688 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T703 | I703 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| C712 | G712 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
| Y713 | C713 | Biomuta | DOID:263 / kidney cancer [ cosmic ] |
DAG View