iPTMnet Report for O75326 (SEMA7A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75326 / SEM7A_HUMAN
Protein Name Semaphorin-7A precursor
Gene Name Name: SEMA7A
Synonyms:CD108,SEMAL;
Organism Homo sapiens (Human)

PRO ID PR:O75326
DAG View
PRO Name semaphorin-7A (human)
Definition A semaphorin-7A that is encoded in the genome of human.
Short Label hSEMA7A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75326 (SEMA7A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N105 N-Glycosylation GlyGen   UniProt 20727575, 24190977
N154 N-Glycosylation GlyGen 29391424
N157 N-Glycosylation GlyGen   UniProt 23090970, 20727575, 24190977
N258 N-Glycosylation GlyGen   UniProt 23090970, 20727575, 29391424, ...24190977
S275 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
N330 N-Glycosylation GlyGen   UniProt 20727575
C493 Methylation IEDB 31844290
N602 N-Glycosylation GlyGen   UniProt 10201933
C645 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N105 K105 Biomuta DOID:1612 / breast cancer [ cosmic ]
T296 A296 Biomuta DOID:3571 / liver cancer [ cosmic ]
C645 Y645 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]